Based upon data from the Framingham Offspring Study based out of Harvard curative School, it is clear that there is an epidemic Vitamin D scantness that may increase the risk of heart disease. (A branch for another article; as well as referenced below in prior "updates.") However, few habitancy are aware that there is also a serious epidemic scantness of vitamin E. An editorial that accompanied the largest study on vitamin E in curative history (Am J Clin Nutr 2006 Nov;84(5):1200-7) stated 93% of American men and 96% of American women do not fetch the [pathetically low] recommended dietary discount of 15 Iu of vitamin E per day.
It is clear that we should be taking at least 30 to 50 times that level (400 to 1000 Iu/day) to cut the risk of persisting diseases. Taking this much vitamin E in the literal, form and balance with other vitamins, is both safe and effective; more than the pharmaceutical fellowships would have you believe. However, it is in the economic interest of pharmaceutical fellowships to dissuade the public from taking supplements so that they can be on medications which often do wee to nothing to reverse disease. Other condition practitioners make their living by "educating" others that they can get everything they need from their food alone. The curative investigate indicates otherwise. The whole of vitamin E, as well as other foremost vitamins, required to cut the risk of persisting diseases can only be obtained straight through supplementation.
Vitamine
Tragically many doctors and the lay person have the misconception that vitamins, such as vitamin E supplementation may be harmful. There seems to be prolonged misinformation put out in news media and condition magazines, with regard to the "dangers" of supplementation. Either they are not aware of the curative research, or they are purposefully misleading the public for their own gain. This non-stop effort to persuade habitancy not to supplement, but to get all their antioxidants from their food alone is at minimum unethical, at worst dangerous. Vitamin E seems to be in these detractors line of fire more than any other nutrient, probably because it is the most common supplement used today. With the thousands of curative studies showing the benefits of supplemental vitamin E, how is it that there is still controversy and confusion? The doses of vitamin E that investigate has shown to be of benefit can Only be obtained straight through proper supplementation.
Almost weekly a new study about the benefits of vitamin E is published. Almost all show condition benefits or inherent condition benefits. Because vitamin E is one of the most favorite supplements, it is only when a curative study or article showing a inherent negative supervene it is reported by the media, Either to make headlines, and/or to scare habitancy away from taking this unbelievable vitamin. The negative findings with regard to vitamin E of a few curative reports have Either shown to be excessively biased, restricting other foremost vitamins that work synergistically with vitamin E, poorly designed, or bearing no cause and supervene of vitamin E to a detrimental condition impact. The studies of vitamin E that have shown a true inherent negative impact are few, but of more point it has given us clarity with regard to the synergistic impact of various vitamins as well as the point of the formulation of vitamin E.
Vitamins must work together for optimal benefit:
Studies published many years ago showed that for vitamin E to continue to function as an antioxidant within the body, sufficient levels of vitamin C must be gift to regenerate (donate more electrons) to vitamin E so that it can continue to prevent oxidation of lipids. Any study about vitamin E that restricts the participants from also taking vitamin C is setting up the study to show nothing more than how vitamin E is speedily "used up," and not regenerated to continuously furnish an antioxidant benefit. It tells us nothing about the real benefits that can be obtained from proper supplementation.
The literal, formulation of vitamin E is critical:
Vitamin E is a family of nutrients; alpha, delta, and gamma-tocopherols and tocotrienols. There is a inequity in the middle of the artificial (petroleum-derived) vitamin E, dl apha-tocopherol , and the natural (food-based ) vitamin E, d alpha-tocopherol. Gamma-tocopherol is a essential form of vitamin E needed to cut the oxidation of lipids (cholesterol) in conjunction with alpha-tocopherol. (J Am Copll Cardiol. 1999 Oct:34(4):1208-15, Pro Natl Acad Sci Usa, 1993 Mar 1:90(5):1771-5) In addition, studies have shown that habitancy who supplement solely with vitamin E in the alpha-tocopherol form are at risk to lower the blood levels of a essential form of vitamin E, gamma-tocopherol. (J Nutr. 2003 Oct:133(10):3137-40; J Nutr.1985 Jun:115(6):807-13 ) The midpoint American's blood-stream is five times more rich in alpha-tocopherol than gamma-tocopherol, and that inequity jumps 20-fold among habitancy who take vitamin E as alpha-tocopherol without gamma tocopherol.
In 2007, a negative study about vitamin E (that lingers as the "justification" for the case against vitamin E) highlights the way the public can be mislead to make some poor decisions about supplementation. (Jama Feb 27, 2007). This was a flawed study with flawed data that terminated that vitamins A and E "significantly increased the risk of mortality." This meta-analysis (report) did very wee to help us understand the benefits of vitamin E, but showed us just how data, and the public's opinion, can be manipulated. The authors of this meta-analysis (which is not a study per se, but a tell of former published studies) carefully 815 prior studies with regard to antioxidants, but included the results of only 68 of these studies for analysis. Some of the studies excluded from their article showed essential benefits and discount of mortality from taking supplements. Option bias was glaringly evident. The authors essentially "cherry-picked" the studies they wanted, and ignored others, so that they could come to their desired conclusion: vitamin E can kill you!
The authors were unable to establish any cause and supervene in the middle of supplementation with vitamin E and an increased risk of death, manufacture this a poorly designed study. The elderly habitancy who died could have just as absolutely died from accidents, medications, surgery, etc. ...who knows? One noted researcher described this article a kin to "doing a cholesterol-lowering study without ever measuring cholesterol levels." Furthermore, the midpoint period of the reviewed studies was 2.7 years, so the ridiculous end that the authors wanted the public to believe was that vitamin E could kill you (somehow) in less than 3 years!
The others ignored many studies showing essential benefits derived from supplemental vitamin E. One such study that was ignored by these researchers was the November 10, 2006 study published in the American Journal of Clinical nourishment which is the largest study on vitamin E in curative history measuring alpha-tocopherol in male smokers. (Am J Clin Nutr 2006 Nov;84(5):1200-7) This study followed 29,000 patients for over 19 years, and included over 13,000 deaths, ...making inherent a essential and fair analysis of vitamin E and the risk of death.
This study showed a essential discount in whole mortality in those patients with the highest blood levels of alpha-tocopherol. Specifically, over a 19-year period men with the highest blood levels of alpha-tocopherol showed the following discount in causes of death:
" Prostate Cancer 32% discount of Death
" Ischemic Stroke 37% discount of Death
" Hemorrhagic Stroke 35% discount of Death
" Lung Cancer 21% discount of Death
" Respiratory Illness 42% discount of Death
The authors of this essential and noteworthy study stated: "As a primary fat-soluble antioxidant that protects lipids from peroxidation, alpha-tocopherol is able to scavenge mutagenic free radicals and inhibit the oxidation of Ldl-cholesterol, and the abilities have foremost implications for the arresting of carcinogenesis and atherosclerosis ....alpha-tocopherol also has some foremost functions that are independent of its antioxidant activity, along with modulation of gene expression, enhancements of immune responses , an suppression of tumor angiogenesis."
The researchers additional elaborated that although the patients who enjoyed the greatest condition benefits had higher blood levels of alpha-tocopherol, these same subjects also had the highest levels of gamma-tocopherol, meaning that these habitancy were taking the natural formulation of vitamin E, not dl-alpha-tocopherol without gamma-tocopherol and the tocotrienols. This study, and other essential studies are ignored by the media, and obviously by doctors who are continually visited and educated by pharmaceutical companies.
Certainly, there are tens of thousands of studies reporting the benefits of various nutritional supplements. They are both safe and effective. If doctors and the public were naturally made aware of the poorly designed analyses that denigrate vitamin E supplementation, and the essential studies about the benefits of taking vitamin E, in the form of alpha-tocopherol and gamma-tocopherol (along with delta-tocopherol and the mixed tocotrienols) along with vitamin C and vitamin K, which replenishes the antioxidant abilities of vitamin E, then I believe that not only would habitancy need less medication and cut the economic crisis in the condition care industry, but more importantly habitancy could enjoy the true condition and happiness that can be obtained by eating right, exercise, and proper supplementation with a full spectrum of potential vitamins and minerals.
Vitamin E, in the natural form (as described above), appears to be safe up to at least 2000 Iu per day. I personally take 800 Iu per day of the full spectrum of vitamin E. When I was in curative practice, I recommended at least that much (if not up to 1200 Iu of vitamin E) to patients with diabetes. The natural form of vitamin E, along with co-enzyme Q10, the red grape passage (grape seed passage and resveratrol) and a full spectrum of other antioxidants (quercetin, alpha lipoic acid, turmeric extract, olive extract, green tea extract, etc.), vitamins (B, C, D, and K), and minerals in the chelated form, all lead to safely and significantly cut the risk of heart disease, stroke, cancer, Alzheimer's disease, lung diseases, and Almost every other persisting degenerative disease, as well as slow the aging process, all without the side-effects of drugs.
The Untold Epidemic - Vitamin E deficiency
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